Source: American Society for Aesthetic Plastic Surgery (ASAPS)
| Hyaluronic Acid | Botalinum Toxin | Fat Injections | Collagen | |
| Name | Restylane, Perlane, and Restylane Fine Lines | Botox and Myobloc | Fat Injection | Zyderm and Zyplast |
| What Is It | A substance found in all living organisms | Botulinum toxin type A - produced by Clostridia Botulinum bacteria. | Fat transfer from one part of the body to another | Natural substances derived from purified bovine (cow) collagen |
| How It Works | For volume and shaping | Temporarily relaxes the muscle | Adds volume | Adds volume |
| Injection Areas | Nasolabial folds, forehead wrinkles, smile lines and lips | Forehead, frown lines, crow’s feet and vertical neck bands | Nasolabial folds, frown lines, crow’s feet, lips and facial recontouring | Nasolabial folds, frown lines, crow’s feet and lips |
| Results | Up to 12 months | Up to 6 months | Highly variable: months to years | Up to 6 months |
| Average Cost * | Unknown | $413 per procedure | $1,065 per procedure | $350 per procedure |
| US Availability | No (FDA approval pending for cosmetic use) | Yes | Yes | Yes |
| Back To Work |
No downtime | No downtime | Minor: 1-4 days Extensive: 7-14 days | No downtime |
| Possible Reactions | Swelling, redness, and tenderness | Bruising, redness, droopy eyelid, headache and flu like symptoms | Swelling, bruising and lumpiness | Slight bruising and allergic reactions |
| Other Considerations | None identified at this time | None identified at this time | Requires a donor site (for example, abdomen, buttocks or thighs) | Requires a skin test for allergic reaction – at least one month wait |